Features of free oxidation in liver homogenates of rats in combined action of copper and subtoxic level of stearate potassium and sodium

  • O. V. Lototska
Keywords: potassiumstearate, sodiumstearate, copper sulfate, lipid peroxidation, antioxidant protection.

Abstract

Toxic effects of heavy metals on animals and humans is aggravating the presence of surfactants. The aim of our research was to identify the peculiarities of free radical oxidation and antioxidant protection in the use of drinking water with subtoxic doses of potassium and sodium stearates in combination with copper on the body of warmblooded animals, such as the liver of experimental rats. Analysis of indicators allows asserting that in experimental rats liver homogenate observed activation of free radical oxidation, the intensity of which depended on the concentration of stearates in water. More pronounced changes were in animals that consumed water with potassium stearate.The action of potassium stearate observed inhibition of antioxidant systems while under the influence of sodium stearate – its activation. Changes in performance were more pronounced in combination stearates with copper.

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Published
2016-11-21
How to Cite
Lototska, O. V. (2016). Features of free oxidation in liver homogenates of rats in combined action of copper and subtoxic level of stearate potassium and sodium. Medical and Clinical Chemistry, (3), 69-74. https://doi.org/10.11603/mcch.2410-681X.2016.v0.i3.6948
Section
ORIGINAL INVESTIGATIONS