Features of lymphocytes in the blood a patient with basal-like breast cancer South-East Ukraine

Authors

  • T. Yu. Pohorila
  • N. F. Shchurov
  • S. M. Pashchenko

DOI:

https://doi.org/10.11603/mcch.2410-681X.2016.v0.i2.6663

Keywords:

breast cancer, lymphoсytes, chemoradiotherapy.

Abstract

Lymphocytes are important in antitumor immunity. Therefore, the estimate of the magnitude of lymphocytes, could be used to determine the protective capabilities of the organism basal-like breast cancer patients. The purpose of the study: building a morphological features peripheral blood lymphocytes of patients with basal-like breast cancer South-East Ukraine, receiving comprehensive chemoradiotherapy. It was found that treatment BLT changes the structure of peripheral blood lymphocytes. After the comprehensive treatment of peripheral blood lymphocytes of patients significantly increased in size, they decreased nuclear-cytoplasmic ratio. For definitions immune status of patients basal-like breast cancer no small role played by morphological characteristics of lymphocytes in the peripheral blood before and after complex treatment.

References

Abramov, M. H. (1998). Hematolohycheskyy atlas. M, 280.

Sokolova, E. Y. (1998). Klynycheskaya ymmunolohyya. rukovodstvo dlya vrachey. pod red. E. Y. Sokolova. M. Medytsyna, 272 .

Petrov, R. V. (1987). Ymmunolohyya. M. Medytsyna, 416.

Vykhrev, D. V., Ledvanov, M. Yu, & Stukova, N. Yu. (2003). Metod svobodnoho kletochnoho эlektroforeza lymfotsytov krovy v kachestve otsenochnoho kryteryya ymmunokorrelyruyushchey teratyy tsykloferonom. Vestn. Sankt-Peterburhskoy Hosudarstvennoy medytsynskoy akademyy ym. Y. Y. Mechnykova, ½, 93–97.

Kazmyrchuk, V. E., & Koval'chuk, L. V. (2006). Klynycheskaya ymmunolohyya y allerholohyya. Vynnytsa. NOVA KNYHA, 526.

Koval'chuk, L. Y., Mal'tsev, D. V., Voytyuk, T. V., Sydorenko, E. Y. (2008). Tsytolohycheskye osobennosty lymfotsytov u bol'nykh s aktyvnoy herpetycheskoy ynfektsyey: vozmozhnosty ranney skrynynhovoy dyahnostyky. Klinich. Imunolohiya. Alerholohiya. Infektolohiya, 3, 55–58.

Hunt, J. S., Petroff, M .G., Mc. Intise, К. Р., & Ober, C. (2005). HLA – G and immune toberance in pregnancy. FASEB J. 19, 681–693.

Koido, S. (2004). Clinical immunology. Clin. Immunol. 113 (3), 9.

Published

2016-07-15

How to Cite

Pohorila, T. Y., Shchurov, N. F., & Pashchenko, S. M. (2016). Features of lymphocytes in the blood a patient with basal-like breast cancer South-East Ukraine. Medical and Clinical Chemistry, (2), 5–9. https://doi.org/10.11603/mcch.2410-681X.2016.v0.i2.6663

Issue

Section

ORIGINAL INVESTIGATIONS