Effects of selenium-zinc-lipid substances from Chlorella vulgaris Biej. on oxidative and tnergy status of rats

  • H. B. Vinyarska
  • P. H. Lykhatskyi
  • O. I. Bodnar
  • L. S. Fira
  • V. V. Grubinko
Keywords: selenium, zinc-lipid substance, Chlorella vulgaris Biej., оxidative processes, antioxidant status, energy metabolism, rats.

Abstract

There were obtained and allocated stable selen-lipid and selen-zinc-lipid substances in a result of incubation of unicellular algae Chlorella vulgaris Biej. In aquaculture with sodium selenite and zinc sulfate their influence on oxidative and energetic status of healthy rat was investigated. There were suppressed prooxidative processes, activated antioxidant status, succinate dehydrogenase and cytochrome oxidase activity and glutamate dehydrogenase way of formation of glutamate were increased when substance at a dose of 0.4 mcg of selenium, 2.5 mcg of zinc and 0.5 mg of lipid per 1 ml of 1 % starch-water suspensions was introduced in organisme of healthy rats. Also it contributed of formation and functioning of the active components of the antioxidant system – catalase, ceruloplasmin, reduction glutathione in a liver and in a blood serum of experimental animals.

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Published
2015-12-29
How to Cite
Vinyarska, H. B., Lykhatskyi, P. H., Bodnar, O. I., Fira, L. S., & Grubinko, V. V. (2015). Effects of selenium-zinc-lipid substances from Chlorella vulgaris Biej. on oxidative and tnergy status of rats. Medical and Clinical Chemistry, 17(4). https://doi.org/10.11603/mcch.2410-681X.2015.v17.i4.5674
Section
ORIGINAL INVESTIGATIONS