ANALYSIS OF THE MINERAL COMPOSITION OF HERBAL ANTIDIABETIC MIXTURES

Authors

  • A. O. Savych I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY
  • S. M. Marchyshyn I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY

DOI:

https://doi.org/10.11603/mcch.2410-681X.2020.v.i2.11364

Keywords:

macroelements, microelements, herbal antidiabetic mixtures, atomic absorption spectroscopy

Abstract

Introduction. Diabetes mellitus is a global social health problem due to the rapid spread of the disease and the development of serious complications in the form of diabetic angiopathies, which significantly reduce the qua­lity and life expectancy of patients. In order to solve this problem, it is necessary to optimize the existing pharmacotherapy, in particular through phytomixtures, that will be able to influence on different links of the pathogenetic mechanism of development of diabetes mellitus and its complications due to a wide range of biologically active substances. In this regard, minerals deserve special attention, as many of them are involved in the regulation of carbohydrate metabolism.

The aim of the study – to learn the mineral composition of the herbal mixtures, which are used in folk medicine for the prevention and treatment of diabetes mellitus.

Research Methods. Determination of the qualitative composition and quantitative content of macro- and microelements was performed by atomic absorption spectroscopy with atomization in an air-acetylene flame.

Results and Discussion. During the study, it was detected and established the quantitative content of 5 macro- and 4 microelements in the herbal antidiabetic mixtures No. 3, No. 4, No. 7, No. 13 and No. 19. According to the results of the study, it was found the highest content of Na in the herbal antidiabetic mixture No. 4; K – No. 4 and No. 7; Fe – No. 4 and No. 9; Mg – No. 3 and No. 19; Ca – No. 4 and No. 19. Among the microelements, which have a significant impact on the development, treatment and course of diabetes, it was established the highest content of Zn in the herbal antidiabetic mixture No. 13 and No. 7; Cr – No. 7 and No. 19; Mn – No. 19; Cu – No. 4.

Conclusions. The results of the study allow predict the pronounced hypoglycemic activity of antidiabetic mixtures by the pathogenetic mechanism of action.

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Published

2020-08-25

How to Cite

Savych, A. O., & Marchyshyn, S. M. (2020). ANALYSIS OF THE MINERAL COMPOSITION OF HERBAL ANTIDIABETIC MIXTURES. Medical and Clinical Chemistry, (2), 81–86. https://doi.org/10.11603/mcch.2410-681X.2020.v.i2.11364

Issue

Section

ORIGINAL INVESTIGATIONS