Clinico-morphological features of complicated colon cancer in patients after surgical interventions

Authors

DOI:

https://doi.org/10.11603/2414-4533.2026.3.16622

Keywords:

colon cancer, Hartmann’s operation, acute intestinal obstruction, colonic bleeding, paracolonic abscess, peritonitis

Abstract

The aim of the work: to improve the results of treatment of complicated colon cancer by comparative analysis of clinical and morphological features of patients of different age groups after emergency surgical interventions for complicated colon cancer.

Materials and Methods. The retrospective cohort study included 227 patients who underwent emergency resections for complicated colon cancer (CC) from 2021 to 2026 at the Pirogov Vinnytsia Regional Clinical Hospital and the Podilsky Regional Center of Oncology of the Vinnytsia Regional Council. 227 patients were included in the study. There were two groups of patients: I group – up to 60 years, II group – 60 years and older. In the II group, two subgroups were distinguished: patients aged 60 to 74 years and patients 75 years and older. The primary point of the study was an assessment of postoperative complications according to the Clavien – Dindo classification within 30 days after surgery. The secondary point was the study of oncological adequacy of the operation.

Results. Group I included 47 (20.7 %) patients, group II – 180 (79.3 %) patients. High comorbidity was more common in group II (46.8 and 100 %). A difference was found between the groups by T-status: in group I there were more cases of T2–T3 (76.6 vs. 46.7 %), while in group II – T4 (53.3 vs. 23.4 %). The majority of patients in group I had pN2 status (68.1 %), in group II – the pN1 status prevailed (70 %). In group II, there were more oncologically inadequately performed operations: 54 (30 %) vs. group I – 2 (4.3 %). The main factors that influenced the radicality of the performed operation: type of urgent complication; type of operation (Hartmann type operation); comorbidity; physical status of patients according to ASA; tumor localization. The results obtained indicate that the clinical and morphological features of patients with complicated CC significantly depend on age. Elderly and senile patients were more likely to have high comorbidity, worse ASA physical status, and less oncological radicality of surgical interventions, while patients younger than 60 years were more likely to have more pronounced metastatic involvement of regional lymph nodes.

Сonclusions. Age-related differences in clinical and morphological characteristics of patients with complicated colon cancer have been established, which must be taken into account when choosing the scope of emergency surgery and assessing its oncological adequacy.

Author Biographies

  • Volodymyr Shaprynskyi, National Pirogov Memorial Medical University, Vinnytsya

    MD, DSc (Medicine), Professor, Head of Department of Surgery No. 1 with a Urology Course

  • Oleksii Kaminskyi, National Pirogov Memorial Medical University, Vinnytsya

    PhD (Medicine), Associate Professor of Department of Surgery No. 1 with a Urology Course

  • Oleh Vorovskyi, National Pirogov Memorial Medical University, Vinnytsya

    MD, DSc (Medicine), Professor of Department of Surgery No. 1 with a Urology Course

  • Volodymyr Dronenko, National Pirogov Memorial Medical University, Vinnytsya

    PhD (Medicine), Associate Professor of Department of Oncology, X-ray diagnostics and Therapy

  • Yurii Myronyshen, National Pirogov Memorial Medical University, Vinnytsya

    Assistant Professor of Department of Surgery No. 1 with a Urology Course

  • Oleksandr Chernychenko, National Pirogov Memorial Medical University, Vinnytsya

    Assistant Professor of Department of Surgery No. 1 with a Urology Course

  • Mykhailo Verba, National Pirogov Memorial Medical University, Vinnytsya, Communal Non-Profit Enterprise “Podilsky Regional Center of Oncology of the Vinnytsia Regional Council”, Vinnytsia, Ukraine

    Intern in Surgery

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Published

2026-09-30

Issue

No. 3 (2026)

Section

Original investigations

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Copyright (c) 2026 Володимир Шапринський, Олексій Камінський, Олег Воровський, Володимир Дроненко, Юрій Миронишен, Олександр Черниченко, Михайло Верба

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How to Cite

Clinico-morphological features of complicated colon cancer in patients after surgical interventions. (2026). Hospital Surgery. Journal Named by L.Ya. Kovalchuk, 3, 17-27. https://doi.org/10.11603/2414-4533.2026.3.16622