Diagnosis and management of pelvic fracture urethral injuries in men: a literature review

Authors

DOI:

https://doi.org/10.11603/2414-4533.2026.2.16437

Keywords:

pelvic fracture urethral injury, PFUI, pelvic fracture urethral distraction defect, PFUD, retrograde urethrography, primary urethral realignment, urethral stricture, anastomotic urethroplasty, reconstructive urology, combat trauma

Abstract

The aim of the work: to analyze scientific publications on the diagnosis and treatment of urethral distraction injuries in pelvic fractures, as well as to summarize current issues on this problem.

Materials and Methods. The analysis included randomized controlled trials, prospective and retrospective cohort studies, systematic reviews, and meta-analyses. Pelvic fractures in men are the result of high-energy trauma and pose a particular clinical problem in wartime. One of the most severe complications is pelvic fracture urethral injury (PFUI), which in the acute phase may lead to urinary outflow obstruction, urinary extravasation, and infectious or septic complications, while in the long term it is associated with urethral stricture, erectile dysfunction, and urinary incontinence. As PFUI predominantly affects young patients, its consequences have a substantial impact on work capacity and overall quality of life. This review summarizes current data on the epidemiology, pathophysiology, and mechanisms of PFUI, as well as the anatomical prerequisites for the development of distraction defects. The relationship between pelvic fracture patterns, shear forces, and the risk of urethral injury is analyzed, and contemporary concepts regarding the typical location of rupture in adults and the differences observed in children are presented. The clinical manifestations of PFUI are described, with emphasis on the fact that the absence of urethrorrhagia does not exclude urethral injury.

Results. Retrograde urethrography remains the diagnostic standard for PFUI in the acute setting, allowing accurate assessment of the level and extent of injury. In selected cases during delayed management, magnetic resonance imaging may be useful for detailed anatomical evaluation and for planning reconstructive surgery. The primary goal of acute management is rapid and safe urinary diversion. Suprapubic cystostomy is considered the baseline approach, whereas primary urethral realignment may be applied selectively in hemodynamically stable patients with appropriate expertise. Regardless of the initial strategy, a significant proportion of patients develop urethral stricture within the first year, necessitating prolonged follow-up. In the delayed setting, the gold standard for the treatment of urethral distraction defects is delayed anastomotic perineal urethroplasty performed after completion of tissue healing.

Conclusions. This review highlights the importance of early referral to specialized reconstructive urology centers and avoidance of repeated low-efficacy endoscopic procedures, as the first reconstructive operation largely determines long-term functional outcomes.

Author Biographies

  • Artem Kobirnichenko, National Military Medical Clinical Center “Main Military Clinical Hospital”, Kyiv, Ukraine

    PhD (Medicine), Chief Consultant of Urological Department of Urology Clinic

  • Nikita Svystak, Ukrainian Military Medical Academy, Kyiv, Uraine

    Lecturer at the Department

References

Kobirnichenko AA. Diagnosis of gunshot injuries to the male urethra in combat conditions. Literature review. CAMM. 2025 Oct.15; 32(2):23-7. DOI: 10.32751/2310-4910-2025-32-2-02. DOI: https://doi.org/10.32751/2310-4910-2025-32-2-02

Horiguchi A. Management of male pelvic fracture urethral injuries: Review and current topics. Int J Urol. 2019 Jun.; 26(6):596-607. DOI: 10.1111/iju.13947. DOI: https://doi.org/10.1111/iju.13947

Shudrak АА, Kondratskyi YM, Zarutskyi YL, Beznosenko AP, Burluka VV, Badiuk МІ, Turchak VO, Pepenin МО, Shudrak YA, Horodetskyi AV. Comprehensive management of combined pelvic fractures and extraperitoneal rectal injuries in combat trauma: clinical experience and outcomes. UJMM [Internet]. 2025 Mar.31 [cited 2026 Jan.2]; 6(1):113-20. Available from: https://ujmm.org.ua/index.php/journal/article/view/516. DOI: https://doi.org/10.46847/ujmm.2025.1(6)-113

Gomez RG, Mundy T, Dubey D et al. SIU/ICUD consultation on urethral strictures: pelvic fracture urethral injuries. Urology. 2014; 83: S48-58. DOI: 10.1016/j.urology.2013.09.023. DOI: https://doi.org/10.1016/j.urology.2013.09.023

Kassiri B, Zhang TR, Alford AV, et al. Management of Pelvic Trauma-Associated Urethral Injury in Men. Curr Surg Rep. 2023; 11:243-50. DOI: 10.1007/s40137-023-00365-w. DOI: https://doi.org/10.1007/s40137-023-00365-w

Mundy AR, Andrich DE. Urethral trauma. Part I: introduction, history, anatomy, pathology, assessment and emergency management. BJU Int. 2011; 108: 310-27. DOI: 10.1111/j. 1464-410X.2011.10339.x. DOI: https://doi.org/10.1111/j.1464-410X.2011.10339.x

Chung PH, Wessells H, Voelzke BB. Updated outcomes of early endoscopic realignment for pelvic fracture urethral injuries at a level 1trauma center. Urology. 2018; 112:191-7. DOI: 10.1016/j.urology.2017.09.032. DOI: https://doi.org/10.1016/j.urology.2017.09.032

Trufanov II, Mikheiev IO, Trybushnyi OV, ZholudevОO. Specialized surgical treatment of unstable pelvic fractures within the closed combat-related pelvic trauma at military hospital. UJMM [Internet]. 2025 Mar.31 [cited 2026 Feb.11]; 6(1):194-01. Available from: https://ujmm.org.ua/index.php/journal/article/view/528. DOI: https://doi.org/10.46847/ujmm.2025.1(6)-194

Bjurlin MA, Fantus RJ, Mellett MM, Goble SM. Genitourinary injuries in pelvic fracture morbidity and mortality using the National Trauma Data Bank. J Trauma 2009; 67:1033-9. DOI:10.1097/TA.0b013e3181bb8d6c. DOI: https://doi.org/10.1097/TA.0b013e3181bb8d6c

Andrich DE, Day AC, Mundy AR. Proposed mechanisms of lower urinary tract injury in fractures of the pelvic ring. BJU Int. 2007; 100:567-73. DOI: 10.1111/j.1464-410X.2007.07020.x. DOI: https://doi.org/10.1111/j.1464-410X.2007.07020.x

Myers JB, McAninch JW. Management of posterior urethral disruption injuries. Nat. Clin. Pract. Urol. 2009; 6:154-63. DOI: 10.1038/ncpuro1319. DOI: https://doi.org/10.1038/ncpuro1319

Bhatt NR, Merchant R, Davis NF, et al. Incidence and immediate management of genitourinary injuries in pelvic and acetabular trauma: a 10-year retrospective study. BJU Int. 2018; 122:126-32. DOI:10.1111/bju.14161. DOI: https://doi.org/10.1111/bju.14161

Gomez RG, Scarberry K. Anatomy and techniques in posterior urethroplasty. Transl. Androl. Urol. 2018; 7:567-79. DOI:10.21037/tau.2018.03.05. DOI: https://doi.org/10.21037/tau.2018.03.05

Mouraviev VB, Santucci RA. Cadaveric anatomy of pelvic fracture urethral distraction injury: most injuries are distal to the external urinary sphincter. J. Urol. 2005; 173:869-72. DOI: 10.1097/01.ju.0000152252.48176.69. DOI: https://doi.org/10.1097/01.ju.0000152252.48176.69

Mundy AR, Andrich DE. Urethral trauma. Part II: types of injury and their management. BJU Int. 2011; 108:630-50. DOI:10.1111/j.1464-410X.2011.10340.x. DOI: https://doi.org/10.1111/j.1464-410X.2011.10340.x

Joshi PM, Kulkarni SB. Management of pelvic fracture urethral injuries in the developing world. World J Urol. 2020 Dec.; 38(12):3027-34. DOI: 10.1007/s00345-019-02918-0. DOI: https://doi.org/10.1007/s00345-019-02918-0

Lückhoff C, Mitra B, Cameron PA, Fitzgerald M, Royce P. The diagnosis of acute urethral trauma. Injury. 2011 Sep; 42(9):913-6. DOI: 10.1016/j.injury.2010.08.007. DOI: https://doi.org/10.1016/j.injury.2010.08.007

Martinez-Pineiro L, Djakovic N, Plas E et al. EAU guidelines on urethral trauma. Eur. Urol. 2010; 57:791-803. DOI: 10.1016/j.eururo.2010.01.013. DOI: https://doi.org/10.1016/j.eururo.2010.01.013

Morey AF, Brandes S, Dugi DD, et al. Urotrauma: AUA guideline. J. Urol. 2014; 192:327-35. DOI: 10.1016/j.juro.2014.05.004. DOI: https://doi.org/10.1016/j.juro.2014.05.004

Wessells H, Angermeier KW, Elliott S, et al. Male urethral stricture: American Urological Association Guideline. J. Urol. 2017; 197:182-90. DOI: 10.1016/j.juro.2016.07.087. DOI: https://doi.org/10.1016/j.juro.2016.07.087

Barrett K, Braga LH, Farrokhyar F, Davies TO. Primary realignment vs suprapubic cystostomy for the management of pelvic fracture-associated urethral injuries: a systematic review and meta-analysis. Urology. 2014; 83:924-9. DOI: 10.1016/j.urology.2013.12.031. DOI: https://doi.org/10.1016/j.urology.2013.12.031

Koraitim MM. Effect of early realignment on length and delayed repair of postpelvic fracture urethral injury. Urology. 2012; 79:912-5. DOI: 10.1016/j.urology.2011.11.054. DOI: https://doi.org/10.1016/j.urology.2011.11.054

McCormick BJ, Keihani S, Hagedorn J, Selph JP, Figler BD, Johnsen NV, da Silva RD, Broghammer JA, Gupta S, Miller B, Burks FN, Eswara J, Osterberg EC 3rd, Carney KJ, Erickson BA, Gretzer MB, Chung PH, Harris CR, Murphy GP, Rusilko P, Shridharani A, Benson C, Alwaal A, Blaschko SD, Breyer BN, Amend GM, McKibben M, Elliott SP, Schwartz IW, Simhan J, Vanni AJ, Moses RA, Myers JB. A multicenter prospective cohort study of endoscopic urethral realignment versus suprapubic cystostomy after complete pelvic fracture urethral injury. J Trauma Acute Care Surg. 2023 Feb. 1; 94(2):344-49. DOI: 10.1097/TA.0000000000003774. DOI: https://doi.org/10.1097/TA.0000000000003774

Koraitim MM. Optimising the outcome after anastomotic posterior urethroplasty. Arab. J. Urol. 2015; 13:27-31. DOI: 10.1016/j.aju.2014.12.006. DOI: https://doi.org/10.1016/j.aju.2014.12.006

Horiguchi A, Shinchi M, Masunaga A, Ito K, Asano T, Azuma R. Do transurethral treatments increase the complexity of urethral strictures? J. Urol. 2018; 199:508-14. DOI: 10.1016/j.juro.2017.08.100. DOI: https://doi.org/10.1016/j.juro.2017.08.100

Gaspar SS, Ferreira ND, Oliveira T, Oliveira P, Dias JS, Lopes TM. Magnetic resonance imaging and pelvic fracture urethral injuries. Urology. 2017; 110:9-15. DOI: 10.1016/j.urology.2017.06.041. DOI: https://doi.org/10.1016/j.urology.2017.06.041

Xu YM, Sa YL, Fu Q, Zhang J, Jin SB. Surgical treatment of 31 complex traumatic posterior urethral strictures associated with urethrorectal fistulas. Eur. Urol. 2010; 57:514-20. DOI: 10.1016/j.eururo.2009.02.035. DOI: https://doi.org/10.1016/j.eururo.2009.02.035

Pratap A, Agrawal C, Pandit R, Sapkota G, Anchal N. Factors contributing to a successful outcome of combined abdominal transpubic perineal urethroplasty for complex posterior urethral disruptions. J. Urol. 2006; 176:2514-7. DOI: 10.1016/j.juro.2006.08.016. DOI: https://doi.org/10.1016/j.juro.2006.08.016

Koraitim MM. On the art of anastomotic posterior urethroplasty: a 27-year experience. J. Urol. 2005; 173:135-9. DOI: 10.1097/01.ju.0000146683.31101.ff. DOI: https://doi.org/10.1097/01.ju.0000146683.31101.ff

Gupta NP, Mishra S, Dogra PN, Yadav R, Seth A, Kumar R. Transpubic urethroplasty for complex posterior urethral strictures: a single center experience. Urol. Int. 2009; 83:22-6. DOI: 10.1159/000224863. DOI: https://doi.org/10.1159/000224863

Bhagat SK, Gopalakrishnan G, Kumar S, Devasia A, Kekre NS. Redo-urethroplasty in pelvic fracture urethral distraction defect: an audit. World J. Urol. 2011; 29:97-101. DOI: 10.1007/s00345-010-0524-8. DOI: https://doi.org/10.1007/s00345-010-0524-8

Koraitim MM. Predictors of surgical approach to repair pelvic fracture urethral distraction defects. J. Urol. 2009; 182:1435-9. DOI: 10.1016/j.juro.2009.06.022. DOI: https://doi.org/10.1016/j.juro.2009.06.022

Fu Q, Zhang YM, Barbagli G et al. Factors that influence the outcome of open urethroplasty for pelvis fracture urethral defect (PFUD): an observational study from a single high-volume tertiary care center. World J. Urol. 2015; 33:2169-75. DOI: 10.1007/s00345-015-1533-4. DOI: https://doi.org/10.1007/s00345-015-1533-4

Horiguchi A, Shinchi M, Ojima K et al. Single-surgeon series of delayed anastomotic urethroplasty for pelvic fracture urethral injury: an analysis of surgical and patient-reported outcomes of a 10-year experience in a Japanese referral center. World J. Urol. 2019. DOI: 10.1007/s00345-019-02630-z. DOI: https://doi.org/10.1007/s00345-019-02630-z

Koraitim MM. Failed posterior urethroplasty: lessons learned. Urology. 2003; 62:719-22. DOI: 10.1016/s0090-4295(03)00573-9. DOI: https://doi.org/10.1016/S0090-4295(03)00573-9

Blaschko SD, Sanford MT, Schlomer BJ, et al. The incidence of erectile dysfunction after pelvic fracture urethral injury: a systematic review and metaanalysis. Arab. J. Urol. 2015; 13:68-74. DOI: 10.1016/j.aju.2014.09.004. DOI: https://doi.org/10.1016/j.aju.2014.09.004

Chung PH, Gehring C, Firoozabadi R, Voelzke BB. Risk stratification for erectile dysfunction after pelvic fracture urethral injuries. Urology. 2018; 115:174-8. DOI: 10.1016/j.urology.2018.01.035. DOI: https://doi.org/10.1016/j.urology.2018.01.035

Koraitim MM. Predictors of erectile dysfunction post pelvic fracture urethral injuries: a multivariate analysis. Urology. 2013; 81:1081-5. DOI: 10.1016/j.urology.2012.12.040. DOI: https://doi.org/10.1016/j.urology.2012.12.040

Fu Q, Zhang J, Sa YL, Jin SB, Xu YM. Recurrence and complications after transperineal bulboprostatic anastomosis for posterior urethral strictures resulting from pelvic fracture: a retrospective study from a urethral referral centre. BJU Int. 2013; 112:E358-63. DOI: 10.1111/bju.12171. DOI: https://doi.org/10.1111/bju.12171

Mundy AR. Words of wisdom. Re: outcome of dorsal buccal graft urethroplasty for recurrent urethral strictures. Eur. Urol. 2009; 55:991-2. DOI: 10.1016/j.eururo.2009.01.011. DOI: https://doi.org/10.1016/j.eururo.2009.01.011

Published

2026-05-29

Issue

Section

Reviews

How to Cite

Diagnosis and management of pelvic fracture urethral injuries in men: a literature review. (2026). Hospital Surgery. Journal Named by L.Ya. Kovalchuk, 2, 92-101. https://doi.org/10.11603/2414-4533.2026.2.16437