Hybrid surgical tactics in patients with persistent microflora as one of the keys to effective wound healing

Abstract

The aim of the work: to improve the quality of life of patients in the acute phase of wound healing, accompanied by persistent microflora, and to reduce the length of hospital stay.

Materials and Methods. In the conditions of Kyiv City Clinical Hospital No. 1, 38 patients were treated, of whom diabetes mellitus (DM) occurred in 17 cases, and 21 patients were without endocrine pathology. This population of patients had microflora resistant to antibacterial drugs. A comprehensive examination of patients with wound healing processes includes a combination of clinical (wound edge biopsy), laboratory (sampling of wound secretions for microbiological analysis) and instrumental methods (Dopplerography, angiography) to assess the condition of the wound, blood supply and general condition of the body. An electrocardiogram, ultrasound scanning of the heart, X-ray of the lungs and bones of the extremities, and thermometry were also used.

Results. The study reasonably describes that combined treatment with probiotics and balloon dilation significantly improves the healing dynamics in patients with various endocrine diseases, which allows to shorten their hospital stay and reduce the acute phase of inflammation. Balloon dilation was found to be important for improving microcirculation, especially in patients with impaired blood circulation, which contributes to faster tissue recovery. Thus, this hybrid surgical tactic is a promising approach in the treatment of patients with persistent wound microflora, especially in those patients who have comorbid conditions.

Conclusions. The use of hybrid surgical tactics and probiotic therapy has demonstrated significant effectiveness in the treatment of wounds with persistent bacterial microflora, especially in patients with diabetes mellitus both clinically and laboratory.