THE CONTENT OF CADMIUM AND ZINC IN THE ECOSYSTEM OF CISCARPATHIAN REGION AND THE IMPACT OF CADMIUM INTOXICATION ON THE TRACE ELEMENT STATUS OF THE BODY OF EXPERIMENTAL ANIMALS
Introduction. Among the measures that should ensure the protection of human health and the environment of its habitat from man-made metals, control over the level of metal content in soil, water, human organism and animals plays an important role.
The aim of the study – to carry out a comparative analysis of the level of cadmium and zinc in the soils and reservoirs of the plain, foothill and mountainous areas of the Precarpathian region, as well as the study of the influence of cadmium intoxication on the microelement composition of the liver and kidneys of experimental animals.
Research Мethods. The object of research was the soils and reservoirs of different geographical zones of Ciscarpathian. Cadmium intoxication was modeled on white male rats, which were divided into two groups: the control and the experimental, which intramuscularly injected cadmium chloride in a dose of 1/10 LD50. The concentration of trace elements in the objects of the environment, organs and tissues of experimental animals was determined by the atomic absorption spectrophotometry method on a spectrophotometer C - 115 PC.
Results and Discussion. The paper presents the results of the content of cadmium and zinc in the soil and drinking water of the plain, foothill and mountainous regions of the region. It was established that in the soil the level of cadmium and zinc in all investigated zones is within the limits of normative indicators. However, the results on the control of cadmium in drinking water indicates an increase in the concentration of cadmium in excess of the maximum permissible norms by 1.5–2 times in plain and foothill areas, and the minimum level – in mountainous areas. Such results encourage the study of the effects of cadmium intoxication on the body of experimental animals. The obtained data indicate that in the body of experimental animals, which continued to drink potable water with high cadmium content there is accumulation in the liver and kidneys of cadmium.
Conclusions. Significant differences in the content of cadmium and zinc in soils and water of the plain, foothill and mountainous areas of the Carpathian region are established. It has been determined that in the organism of experimental animals, cadmium intoxication leads to accumulation of cadmium in the liver and kidneys, which is accompanied by a violation of the level of essential elements of zinc and copper.
Vorozhenko,V.V., Skalskyi, Yu.M. (2011). Hihiienichna otsinka ryzykiv vplyvu neradiatsiinykh antropohennykh chynnykiv na stan zdorovia naselennia Ukrainy [Hygienic estimation of the risks of non-radiation anthropogenic factors influence on the health status of the population of Ukraine]. Odeskyi medychnyi zhurnal – Odesa Medical Journal, 5 (127), 4-8 [in Ukrainian].
Hryhorenko, L.V., Shtepa, O.P. (2010). Ekoloho-hihiienichna otsinka tekhnohennoho zabrudnennia gruntu antropohennykh landshaftiv mista Dnipropetrovska kadmiiem i svyntsem [Ecological-hygienic estimation of technogenic pollution of soil of anthropogenic landscapes of the city of Dnipropetrovsk with cadmium and lead]. Dovkillia ta zdorovia – Environment and Health, 3, 34-37 [in Ukrainian].
Angelova, V., Ivanova, І., Todorov, J.(2010). It lead, cadrnium, zinc and copper bioavailability in the soil-plant-animal system in a pollted area. Sci. World J, 10, 273-285.
Antoniak, H.L., Biletska, L.P., Babych, N.A. (2010). Kadmii v orhanizmi liudyny i tvaryn. Nadkhodzhennia do klityn i yikh akumuliatsiia [Cadmium in humans and animals. Admission to cells and their accumulation].
Biolohichni Studii. Studia Biologica – Biological Studios. Studia Biologica, 4 (2), 127-140 [in Ukrainian].
Barregard, L., Svalander, Ch., Schuts, A. (2011). Cadmium, mercury and lead in kidney cortex of the general Swedish population: A study of biopsies from living kidney donors. Env. Illth Perspective, 213 (2), 199.
Marushko, Yu.V., Tarinska, A.L. (2010). Nakopychennia kadmiiu ta yoho vplyv na orhanizm dytyny [Accumulation of cadmium and its effects on the body of the child]. Zhurnal "Zdorovye rebenka" – Journal "Child’s Health", 5 (26), 49-52 [in Ukrainian].
(2005). DSTU 4287:2004. Yakist gruntu. Vidbyrannia prob [The quality of the soil. Sampling]. Kyiv: Derstandart of Ukraine [in Ukrainian].
(2009). DSTU 4770.3: 2007. Yakist hruntu. Vyznachennia vmistu rukhomykh spoluk kadmiiu v grunti v bufernii amoniino-atsetatnii vytiazhtsi z rN 4,8 metodom atomno-absorbtsiinoi spektrofotometrii [Quality of soil. Determination of the content of mobile cadmium compounds in the soil in a buffer ammonio-acetate extract with a pH of 4,8 by atomic absorption spectrophotometry]. Kyiv Derzhspozhyvstandart of Ukraine [in Ukrainian].
(2009). DSTU 4770.2: 2007. Yakist hruntu. Vyznachennia vmistu rukhommkh spoluk tsynku v hrunti v bufernii amoniino-atsetatnii vytiazhtsi z rN 4,8 metodom atomno-absorbtsiinoi spektrofotometrii [Quality of soil. Determination of the content of movements of zinc compounds in the soil in a buffer ammonio-acetate extract with a pH of 4,8 by atomic absorption spectrophotometry]. Kyiv Derzhspozhyvstandart of Ukraine [in Ukrainian].
(2002). DSTU ISO 5667–6–2001. Yakist vody. Vidbyrannia prob. Nastanovy, shchodo vidbyrannia prob vody z richok ta inshykh vodotokiv [Water quality. Sampling Guidelines for sampling water from rivers and other watercourses]. Kyiv: Derstandart of Ukraine [in Ukrainian].
(2010). Derzhavni sanitarni normy ta pravyla 2.2.4-171-10 "Hihiienichni vymohy do vody pytnoi, pryznachenoi dlia spozhyvannia liudynoiu" [State sanitary norms and rules 2.2.4-171-10 "Hygienic requirements for drinking water intended for human consumption"]. Kyiv: Derstandart of Ukraine [in Ukrainian].
Myslyva, T.M. (2013). Svynets i kadmii u hruntakh pryrodnikh ahrolandshaftiv Zhytomyrskoho Polissia [Lead and cadmium in soils of natural agro-landscapes of Zhytomyr Polissia]. Visnyk Zhytomyrskoho natsionalnoho ahrarnoho universytetu – Bulletin of the Zhytomyr National Agrarian University, 1 (1), 36-49 [in Ukrainian].
Horin, M.O., Vasiukov, O.Ye., & Hololobova, O.V. (2010). Kadmii i tsynk u luchnykh travostoiakh kormovoho pryznachennia (ekolohichna otsinka) [Cadmium and zinc in meadow grass fields of forage (ecological assessment)]. Visnyk KhNAU. Hruntoznavstvo – Herald KhNUU. Soil Science, 5, 41-45 [in Ukrainian].
Andrusyshyn, T.O., & Hrubinko, V.V. (2012). Sezonna dynamika vmistu vazhkykh metaliv u vodi ta donnykh vidkladakh richky Zbruch [Seasonal dynamics of heavy metal content in the water and bottom sediments of the Zbruch River]. Visnyk Lvivskoho universytetu. Seriia biolohichna – Visnyk of Lviv University. Biological series, 58, 165-174 [in Ukrainian].
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