QUANTITATIVE CONTENT OF THE AMOUNT OF ORGANIC ACIDS IN THE SERIES OF RAW MATERIALS OF SOME SPECIES OF THE FAMILIES POLYGONACEAE, ROSACEAE AND ASTERACEAE

Authors

  • T. V. Oproshanska NATIONAL UNIVERSITY OF PHARMACY, KHARKIV
  • О. P. Khvorost NATIONAL UNIVERSITY OF PHARMACY, KHARKIV
  • V. V. Kudrіa M. PYROHOV VINNYTSIA NATIONAL MEDICAL UNIVERSITY

DOI:

https://doi.org/10.11603/mcch.2410-681X.2020.v.i3.11543

Keywords:

organic acids, rumex, sanguisorba, rosa, arctium, bidens

Abstract

Introduction. Considering to the physiological activity of organic acids for the human body, the search of new sources of this group of biologically active substances is urgent.

The aim of the study – to determine the quantitative content of organic acids in rhizomes with roots of Rumex confertus, rhizomes with roots of Sanguisorba officinalis, roots of Rosa majalis, roots of Rosa canina, roots of Arctium minus, roots of Arctium tomentosum, herbs of Bidens tripartita.

Research Methods. The quantitative content of organic acids was determined according to the methods given in the monographs of SPhU 2.0 – "Rose hips", in terms of malic amount acid and "Viburnum fruits", in terms of citric acid.

Results and Discussion. Using of the method from the monograph of "Rose hips" led to slightly higher results of determination in the quantitative content of the amount of organic acids in the studied raw materials than the method of the mono­graph "Viburnum fruits". It can be connected with the sample preparation and histological features of the underground organs, which include a significant percentage of woody tissues. At that time, the results of quantitative determination of this group of compounds in series of herbs of Bidens tripartita by two methods was comparable. The quantitative content of the sum of organic acids in different batches of one type of raw material within the use of each technique varied slightly.

Conclusions. For the first time it was carried out a quantitative content of the amount of organic acids in the rhizomes with roots of Rumex confertus, rhizomes with roots of Sanguisorba officinalis, roots of Rosa majalis, roots of Rosa canina, roots of Arctium minus, roots of Arctium tomentosum, herbs of Bidens tripartite with using methodics from the monographs of SPhU 2.0. It was found that the content of the total organic acids in all the objects that were studied was observed when using the method of the monograph "Rose hips", which was the highest in the underground organs of Sanguisorba offi­cinalis and Rumex confertus and amounted to 3.7 % and 3.5 %, respectively. The obtained results will be used in further research.

References

Moskalenko, A.M. & Popova, N.V. (2019). Doslidzhennia orhanichnykh kyslot syrovyny bezsmertnyka prykvitkovoho (Helichrysum bracteatum) [Research of organic acids of raw immortelle bracts (Helichrysum bracteatum)]. Ukrainskyi biofarmatsevtychnyi zhurnal – Ukrainian Biopharmaceutical Journal, 4, 65-69 [in Ukrainian].

Kumar Vinod, Sharma Anket, Bhardwaj Renu & Kumar Thukral Ashwani (2017). Analysis of organic acids of tricarboxylic acid cycle in plants using GC-MS, and system modeling. Journal of Analytical Science and Technology, 8, 20.

Sinichenko, A.V., & Marchyshyn, S.M. (2018). Doslidzhennia orhanichnykh kyslot kultyvovanykh vydiv rodu Primula L. [Research of organic acids of cultivated species of the genus Primula L.]. Abstracts of papers 87-i naukovo-prakt. konf. studentiv ta molodykh vchenykh z mizhnarodnoiu uchastiu “Innovatsii v medytsyni” – Proceeding of the 87th Scientific Practice. Conf. of Students and Young Scientists with International Participation “Innovations in Medicine”. Ivano-Frankivsk. [in Ukrainian].

Yao Liu, Na Zhang, ShePo Shi Qingqing Song, Jielan Li, Yuelin Song & Peng-Fei Tu. (2018). Simultaneous determination of 14 organic acids in Shenfu injection by hydrophilic interaction chromatography-tandem mass spectrometry. Zhongguo Zhong Yao Za Zhi, 41 (18), 3342-3348.

Joanna Chlopicka, Justyna Dobrowolska-Iwanek, Michal Wozniakiewicz & Pawel Zagrodzki. (2014). Optimization of conditions for organic acid extraction from edible plant material as applied to radish sprouts. Food Analytical Methods, 7 (6), 1323-1327.

Aleksyeyev, I., & Dibrova. A. (2019). Povnyi atlas likarskykh roslyn [Complete atlas of medicinal plants]. [in Ukrainian].

Eungyeong Jang, Kyung-Soo Inn, Young Pyo Jang, Kyung-Tae Lee & Jang-Hoon Lee. (2018). Phytotherapeutic activities of Sanguisorba officinalis and its chemical constituents: A review. The American Journal of Chinese Medicine, 46 (02), 1-20.

Zajczeva, N.V. (2014). Gosudarstvennoye byud­zhetnoye obrazovatelnoe uchrezhdenie vysshego professionalnogo obrazovaniya [Pharmacognostic study and standardization of the roots of horse sorrel (Rumex con­fertus WILLD)]. Candidate’s thesis. Samara State Medical University, Samara [in Russian].

(1987). Gosudarstvennaya farmakopeya SSSR XI izd. Vyp. 1. Obshchie metody analiza [State Pharmacopoeia of the USSR XI ed. Issue 1. General methods of analysis]. Moscow: Meditsina [in Russian].

Oproshanska, T.V., & Khvorost, O.P. (2017). Quantitative content of organic acids and ascorbic acid in the root of plants genus of Аrctium. Zb. naukovykh prats spivrobitnykiv NMAPO im. P. L. Shupyka – Collec­tion of Scientific Works of Employees of NMAPO by P. L. Shupyk, 28, 87-93.

Oproshanska, T.V., Khvorost, O.P., & Ochered­ko, L.V. (2017). Determination of quantitative content of amount of organic acids and ascorbic acid in different series of Rosa majalis and Rosa canina raw materials. Visnik of Pharmacy, 1, 10-13.

Marchyshyn, S., Kudrja, V., & Nakonechna, S. (2018). Investigation of organic acids of Sanguisorba offi­cinalis rhizomes with roots and herb (Sanguisorba offici­nalis L.). The Pharma Innovation Journal, 7 (6), 216-218.

(2016). Derzhavna Farmakopeia Ukrainy. 2-e vyd. Dopovnennia 1. [State Pharmacopoeia of Ukraine. 2nd edition. Appendix 1.]. Kharkiv: Derzhavne pidpryiemstvo “Ukrainskyi naukovyi farmakopejnyi tsentr yakosti likarskykh zasobiv” [in Ukrainian].

(2020). Derzhavna Farmakopeia Ukrainy. 2-e vyd. Dopovnennia 4. [State Pharmacopoeia of Ukraine. 2nd edition. Appendix 41.]. Kharkiv: Derzhavne pidpryiemstvo “Ukrainskyi naukovyi farmakopejnyi tsentr yakosti likarskykh zasobiv” [in Ukrainian].

Published

2020-12-03

How to Cite

Oproshanska, T. V., Khvorost О. P., & Kudrіa V. V. (2020). QUANTITATIVE CONTENT OF THE AMOUNT OF ORGANIC ACIDS IN THE SERIES OF RAW MATERIALS OF SOME SPECIES OF THE FAMILIES POLYGONACEAE, ROSACEAE AND ASTERACEAE. Medical and Clinical Chemistry, (3), 81–86. https://doi.org/10.11603/mcch.2410-681X.2020.v.i3.11543

Issue

Section

ORIGINAL INVESTIGATIONS