RISK FACTORS FOR OSTEOPOROSIS IN WOMEN WITH ARTERIAL HYPERTENSION AND OBESITY, WORKING UNDER UNFAVORABLE PRODUCTION CONDITIONS
DOI:
https://doi.org/10.11603/24116-4944.2018.2.8939Keywords:
postmenopausal period, osteoporosis, arterial hypertension, obesity, unfavorable conditions of productionAbstract
The aim of the study – to learn the risk factors for the development of osteoporosis in women with arterial hypertension and obesity, working in unfavorable production conditions for the prediction and early diagnosis of osteoporosis.
Materials and Methods. There were examined 110 women (mean age 56.2±1.74 years) in postmenopausal period (duration of postmenopause – (6.8±1.9) years). The main group consisted of 80 women with arterial hypertension stage 2 and obesity, who work under the influence of unfavorable factors of production. The control group consisted of 30 practically healthy women. Objective examination, anthropometry, ultrasonic densitometry was carried out. The main risk factors were studied using specially designed questionnaires.
Results and Discussion. The women of the main group demonstrated lower T-test indices (p˂0.05) compared to the control group, which indicates negative effect of unfavorable factors of production on the bone tissue condition and depends on the work experience. The correlation analysis of the main risk factors for osteoporosis and the T-test showed a statistically significant negative feedback between the T-test and unfavorable production factors (r = -0.456, p˂0.001), T-test and work experience under unfavorable production conditions (r = -0.724, p0.001), the T-test and the duration of postmenopause (r = -0.543, p˂0.001), the T-test and duration of arterial hypertension (r = -0.531, p˂0.001), T-test and body mass index (r = -0.592, p˂0.001) and indicates that hypertension, obesity, postmenopause and unfavorable factors of production have summing a negative impact on bone mineral density in female workers.
Conclusions. For the prediction and early diagnosis of osteoporosis, it is necessary to analyze all risk factors for the development of structural and functional changes in bone tissue. This will allow for timely treatment and prevention in the pre-clinical stage of the disease, reduce the risk of fractures and improve the quality of life.
References
Hryhorieva, N.V., Ribina, O.S., Yunusova, S.V., & Povoroz-niuk, V.V. (2011). Likuvalna fizkultura v profilaktytsi i likuvanni osteoporozu ta yoho uskladnen [Training in the prevention and treatment of osteoporosis and its complications]. Bol. Sustavy. Pozvonochnik – Pain. Joints. Vertebral Column, 1, 108-115 [in Ukrainian].
Ermolenko, T.A., Shabliy, T.P., Prutiyan, T.L., & Dobrovolskaya, Ye.A. (2016). Menopausa – faktor riska razvitiya metabolicheskikh narusheniy [Menopause – a risk factor for the development of metabolic disorders]. Mizhnarodna naukovo-praktychna konferentsiia “Suchasni teoretychni i praktychni aspekty zdorovoho sposobu zhyttia” – The Second International Scientific and Practical Conference “Modern Theoretical and Practical Aspects of the Healthy Way of Life”. (рр. 110-112). Odesa [in Russian].
Ermolenko, T.A., & Yamilova, T.N. (2015). Faktory riska razvitiya strukturno-funktsionalnykh izmeneniy kostnoy tkani u zhenshchin [Risk factors for the development of structural and functional changes in bone tissue in women]. Visnyk morskoi medytsyny – Herald of Marine Medicine, 1, 40-43 [in Ukrainian].
Lesnyak, O.M., & Benevolenskaya, L.I. (2012). Osteoporoz: klinicheskiye rekomendatsii [Osteoporosis: Clinical Recommendations]. Moscow [in Russian].
Povoroznуuk, V.V., Grigoryeva, N.V., Orlik, Т.V., Nishkumay, O.I., Dzerovich, N.I., & Balatskaya, N.I. (2014). Osteoporoz v praktike vracha-internista [Osteoporosis in the practice of an internist]. Kyiv [in Ukrainian].
Ihnatiev, О.М. (2016). Suchasni metody diahnostyky, prohnozuvannia, likuvannia ta profilaktyky osteoporozu u pratsivnykiv vyrobnychykh pidpryiemstv: metodychni rekomendatsii MOZ Ukrainy [The modern methods of diagnostics, forecasting, treatment and prevention osteoporosis in workers production manufacture: Methodical recommendations of the Ministry of Health of Ukraine]. Kyiv [in Ukrainian].
Ignatyev, A.M., Lubyanova, I.P., Timoshina, D.P., & Yamilova, T.N. (2009). Mediko-sotsialnaya aktualnost ranney diagnostiki i korrektsii strukturno-funktsionalnykh izmeneniy kostno-myshechnoy sistemy u rabotayushchikh v neblagopriyatnykh usloviyakh [Medico-social relevance of early diagnosis and correction of structural and functional changes in the musculoskeletal system in workers under unfavorable conditions]. Ukraіnskyi medychnyi almanakh – Ukrainian Medical Almanac, 12 (1), 82-85 [in Ukrainian].
Shuba, N.M. (2008). Osteoporoz – aktualna problema XXI stolittia: suchasne uiavlennia pro patohenez і terapiiu [Osteoporosis is an urgent problem of the XXI century: a modern understanding of pathogenesis and therapy]. Ukrainskyi revmatolohichnyi zhurnal – Ukrainian Rheumatological Journal, 32 (2), 5-14 [in Ukrainian].
Yarmolinskaya, M.I. (2014). Postmenopauzalnyy osteoporoz. Klinika, diagnostika, profilaktika, lecheniye [Postmenopausal osteoporosis. Clinic, diagnosis, prevention, treatment]. Moscow: Serebryannye niti [in Russian].
Bagger, Y.Z. (2007). Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se? Osteoporos Int., 18 (4), 505-512.
Crandall, C.J. (2014). Comparative effectiveness of pharmacologic treatments to prevent fractures: an updated systematic review. Ann. Intern. Med., 161, 711-723.
Ignatiev, А.M. (2015). Application exercise depending on the performance index of neuro-spinal and spinal function of degree of compression of the vertebrae in patients with osteoporosis. Journal of Education, Health and Sport., 5 (10), 234-243.
Kanis, J.A. (2008). FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos. Int., 19, 385-397.
Maimoun, L. (2015). Impact of obesity on bone mass throughout adult life: influence of gender and severity of obesity. Bone, 14, 12-44.
Martyn-St James, M.A. (2009). Мeta-analysis of impact exercise on postmenopausal bone loss: the case for mixed loading exercise programmes. Br. J. Sports Med., 43 (12), 898-908.
The Eastern European & Central Asian Regional Audit Epidemiology, Costs & Вurden of Osteoporosis in 2010 (2011). International Osteoporosis Foundation (IOF), 61.
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