RESULTS OF A RETROSPECTIVE ANALYSIS OF THE COURSE OF PREGNANCY, CHILDBIRTH AND PERINATAL OUTCOMES IN WOMEN – INTERNALLY DISPLACED PERSONS WITH A THREAT OF PREGNANCY TERMINATION
DOI:
https://doi.org/10.11603/24116-4944.2024.2.15085Keywords:
pregnancy, spontaneous premature childbirth, premature rupture of membranes, vaginal microbiocenosisAbstract
The aim of the study – to establish the main risk factors for the threat of termination of pregnancy and the development of premature birth in internally displaced women and to develop highly specific criteria for individual prognosis in order to improve perinatal outcomes based on retrospective analysis.
Materials and Methods. A retrospective study of 250 histories of pregnancy and childbirth of women – internally displaced persons, who had a threat of abortion in the Ist and IInd trimesters and premature birth in the gestational period of 22–36 weeks, was conducted. We studied the peculiarities of the course of pregnancy, childbirth of the examined women who were in hospital treatment for the threat of abortion, as well as those who were observed in outpatient health care Sumy city institutions during 2022-2024. The condition of their newborns was also investigated.
Results and Discussion. Important risk factors for premature rupture of membranes (PROM) in preterm pregnancy included the presence of sexually transmitted diseases (χ2=31.188, p=0.001), bacterial vaginosis (χ2=30.913, p=0.0001), a history of abortion and/or preterm birth (χ2=16.62, p=0.0002), acute respiratory viral infections during pregnancy (χ2=16.444, p=0.0002), chronic adnexitis in anamnesis (χ2=11.522, p=0.0031), inflammatory cervical disease (χ2=11.437, p=0.0032), anaemia (χ2=10.815, p=0.0044), isthmic-cervical insufficiency (ІСІ) (χ2=10.345, p=0.0057), chronic pyelonephritis with exacerbation (χ2=9.16, p=0.01), smoking during pregnancy (χ2=10.815, p=0.0044).
Conclusions. The results of a retrospective analysis of 250 cases of preterm birth at 22 to 36 weeks allowed us to identify ways to effectively use existing diagnostic measures to determine readiness for pregnancy and the possibility of prolonging pregnancy to the viability of the newborn. Ways to improve the prevention of preterm birth and the design of further research were identified.
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