A CLINICAL CASE REPORT OF MONDOR'S DISEASE OF THE BREAST

Authors

DOI:

https://doi.org/10.11603/24116-4944.2024.1.14754

Keywords:

breast, acute thrombophlebitis, diagnosis, breast cancer

Abstract

The aim of the study – to describe a rare clinical case of Mondor's disease of the breast, whose clinical symptoms can mimic breast cancer, and to analyze the diagnostic value of different imaging methods in this case.

Materials and Methods. A rare clinical case of Mondor's disease of the breast is described, a clinical examination of the patient was performed with the appointment of the necessary diagnostic methods, patient was treated according to current clinical protocols, and dynamic observation was performed. Assessment of the state of the mammary glands was carried out according to the standardized scale for evaluating the results of mammography, ultrasound and MRI according to the degree of risk of the occurrence of malignant neoplasms of the mammary glands BI-RADS (Breast Imaging-Reporting and Data System). Materials from the scientific databases PubMed, Google Scholar, Web of Science, and Scopus were processed to search for up-to-date information on methods of diagnosing pathology and approaches to treatment.

Results and Discussion. Mondor's disease is a rare pathology of the breast gland, manifested by acute thrombophlebitis of the superficial veins of the front and lateral walls of the chest and epigastrium, in particular, its symptoms can be manifested on the breasts. The report describes a clinical case of Mondor's disease of the left breast in a 40-year-old woman, which occurred after an acute respiratory infection. Clinical symptoms simulated breast cancer. The significance of various diagnostic methods is shown. Mammography turned out to be uninformative in this case. Ultrasound made it possible to visualize the thrombosed superficial vein of the breast. There were no changes in laboratory tests. Conservative treatment (general and local anti-inflammatory) proved to be effective.

Conclusions. Mondor's disease of the breast has a benign course and a favorable prognosis. A number of common symptoms with breast cancer require careful examination of the patient according to current protocols. Ultrasound with doppler is a more informative diagnostic method for this pathology than mammography. Awareness of the possibility of the occurrence of such a rare pathology can prevent the performance of unnecessary biopsy procedures in this case. Given the small frequency of pathology, each described case is interesting for study.

Author Biography

  • L. V. Nitefor, I. Horbachevsky Ternopil National Medical University

    PhD, MD, Assistant Prof. Department of Oncology, Radiation Diagnostics and Therapy and Radiation Medicine; I. Horbachevsky Ternopil National Medical University

References

1. Shchepotin IB, Zotov OS, Zaivelieva IuI, Bezugla MV. Mondor's disease: review and own experience. Klinichna onkolohiia. 2012;6(2).

2. Ben Hamida K, Ghalleb M, Triki A, Jebir I, Makhlouf R, Touinsi H. Mondor's disease of the breast: a case series. J Med Case Rep. 2021;15(1):188. Available from: https://doi.org/10.1186/s13256-021-02708-6

3. Obradovic K, Adzic N, Pavlovic Stankovic D, Petkovic I, Urban V, Milosevic Z. Superficial thrombophlebitis of the breast (Mondor's disease): an uncommon localization of common disease. Clin Med Insights Case Rep. 2020;13:1179547620972414. Available from: https://doi.org/10.1177/1179547620972414

4. Renshaw L, Dixon JM, Anderson J, Turnbull AK. Mondor's disease of the breast: A cutaneous thromboembolic manifestation of COVID-19? Breast. 2022;66:305-309. Available from: https://doi.org/10.1016/j.breast.2022.11.006

5. Goldman A, Wollina U. Mondor's disease after aesthetic breast surgery: a case series and literature review. J Cutan Aesthet Surg. 2018;11(3):132-135. Available from: https://doi.org/10.4103/JCAS.JCAS_69_18

6. Yamaguchi T. Mondor disease of the breast. Cleve Clin J Med. 2022;89(7):371-372. Available from: https://doi.org/10.3949/ccjm.89a.21097

7. Vijayan P, Pang FT. Mondor's disease of the breast in Asia: a forgotten diagnosis for the front-line clinicians—a case report and literature review. Egypt J Radiol Nucl Med. 2023;54:70. Available from: https://doi.org/10.1186/s43055-023-01020-1

8. Pipal DK, Pipal VR. Mondor's disease: a rare cause of chest pain. Cureus. 2022;14(2):e22320. Available from: https://doi.org/10.7759/cureus.22320

9. Seemann LL, Ardon T, Bowie RA, Bullock KC, Clapp ADM. Breast pain differential: Mondor's disease of the breast. J Investig Med High Impact Case Rep. 2024;12. Available from: https://doi.org/10.1177/23247096241246621

10. Yordanov YP. Trauma on a recently augmented breast as a trigger for Mondor's disease. Aesthetic Plast Surg. 2019;43(4):927-929. Available from: https://doi.org/10.1007/s00266-019-01331-7

11. Zeidan M. Mondor disease – breast. Radiopaedia.org. 2024. Available from: https://doi.org/10.53347/rID-98448

12. Rountree KM, Barazi H, Aulick NF. Mondor disease. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538282/

13. Wong SN, Lai LK, Chan PF, Chao DV. Mondor's disease: sclerosing thrombophlebitis of subcutaneous veins in a patient with occult carcinoma of the breast. Hong Kong Med J. 2017;23(3):311-312. Available from: https://doi.org/10.12809/hkmj154699

14. Shabani Z, Pllumi Guli A. Case report of Mondor disease in a 49-year-old Albanian woman. Int J Surg Case Rep. 2024;117:109493. Available from: https://doi.org/10.1016/j.ijscr.2024.109493

15. Hemsing AL, Reikvam H. Mondor's disease after extensive training with Nordic walking. Oxf Med Case Reports. 2019;2019(8):omz075. Available from: https://doi.org/10.1093/omcr/omz075

16. Bastos Mendes JM, Ferreira Gomes JF, Rovisco Branquinho L, Oliveira Carvalho C, Pacheco Mendes PFAP, Carvalho Madaleno JL. Mondor's disease: a rare cause of chest pain. Eur J Case Rep Intern Med. 2020;7(12):001984. Available from: https://doi.org/10.12890/2020_001984

17. Suganthan N, Ratnasamy V. Mondor's disease—a rare cause of chest pain: a case report. J Med Case Rep. 2018;12(1):4. Available from: https://doi.org/10.1186/s13256-017-1530-x

18. Salemis NS, Vasilara G, Lagoudianakis E. Mondor's disease of the breast as a complication of ultrasound-guided core needle biopsy: management and review of the literature. Breast Dis. 2015;35(1):73-76. Available from: https://doi.org/10.3233/BD-140374

19. de Almeida MJ, Guillaumon AT, Miquelin D, Joviliano EE, Hafner L, Sobreira ML, et al. Guidelines for superficial venous thrombosis. J Vasc Bras. 2019;18:e20180105. Available from: https://doi.org/10.1590/1677-5449.180105

20. Faenza M, Pelella T, Antonetti AM, Izzo S, Grella R, Ferraro GA. Mondor's disease as a complication in breast surgery in a male patient. The first ever reported case in literature. Case Rep Plast Surg Hand Surg. 2022;9(1):203-206. Available from: https://doi.org/10.1080/23320885.2022.2121711

Published

2024-04-15

Issue

Section

OBSTETRICS AND GYNECOLOGY

How to Cite

A CLINICAL CASE REPORT OF MONDOR’S DISEASE OF THE BREAST. (2024). Actual Problems of Pediatrics, Obstetrics and Gynecology, 1, 82-86. https://doi.org/10.11603/24116-4944.2024.1.14754