THE ROLE OF HEMODYNAMIC PROCESSES IN CHANGES OF THE UTERUS OF PREGNANT WOMEN WITH PRIMARY ARTERIAL HYPOTENSION

Authors

  • A. Popovytch Danylo Halytsky Lviv National Medical University image/svg+xml
  • L. B. Markin Danylo Halytsky Lviv National Medical University image/svg+xml

DOI:

https://doi.org/10.11603/24116-4944.2018.2.8735

Keywords:

pregnancy, primary arterial hypotension, external tocography, utero-placental hemodynamics

Abstract

The aim of the study – to learn the influence of intrauterine hemodynamic processes on the deliveries of women with primary arterial hypotension.

Materials and Methods. Contractility of the uterus using the method of external tocography in 50 pregnant women during their deliveries and 25 women with uncomplicated course of urgent deliveries was studied. We determined the contractility of the uterus during first period of the delivery – in latent phase-opening of the cervix under 4 cm, 5–6 cm and 7–10 cm. We made dynamic ultrasound examination: transverse size of the regional sinus of placenta (mm). Doplerometric study of utero-placental hemodynamics was made including blood flow in uterinе arterias.

Results and Discussion. In pregnant women with primary arterial hypotension we revealed increase of the latent phase, second period of delivery, so, general duration of the deliveries (p<0.05). When we made comparison of basal intauterinal tonus in women of our control group and the observation group, we revealed decrease in 1.5 times of the basal intrauterine tonus. During the delivery intensity and quantity of the contractions was weaker in 1.5 times in women with primary arterial hypotension and time interval was longer in 1.5–2 times. Uterine activity in latent phase of the delivery was weaker in 3 times, and in active phase – in 1.5 times in comparison with control group. Study of the influence of hemodynamic dysfunction of uterus in women with primary arterial hypotension revealed increase of vasal resistance in right and left uterine arterias, more in right one, which is dominant in the uterine hemodynamics. That provoked increase of the preplacental resistance of blood flow, limitation of blood volume in intervillous space, regional sinus and vasals of the miometry. In pregnant women with primary arterial hypotension: transverse size of regional sinus of placenta was smaller than in control group.

Conclusion. The activation of vasodilation in pregnant women with primary arterial hypotension provokes decrease of systolic and diastolic speed of blood flow in uterine arterias, that causes utero-placental hypoperfusion and slowdown of delivery.

References

Markin, L.B., & Ostrovska, O.V. (2010). Diahnostyka ta korektsiia hemodynamichnykh rozladiv pry zatiazhnomu pershomu periodi polohiv [Diagnostics and corrections disturbances of the maternal-placental circulation of the latent phase of the first labor period]. Pediatriia, akusherstvo ta hinekolohiia – Pediatrics, Obstetrics and Gynecology, 1 (72), 54-57 [in Ukrainian].

Markin, L.B., & Hychka, N.M. (2016). Biofizychni parametry funktsionalnoi systemy maty-platsenta-plid pry fiziolohichnomu perebihu latentnoi fazy pershoho periodu peredchasnykh polohiv [Biophysycal parameters of the functional system uterus-placenta-fetus during the physiological process of latent phase of the first period of preterm delivery]. Aktualni pytannia pediatrii, akusherstva ta hinekolohii – Actual Issues of Pediatrics, Obstetrics and Gynecology, 1, 86-89 [in Ukrainian].

Sidorova, I.S. (2000). Fiziologiya i patologiya rodovoy deyatelnosti [Physiology and pathology of labor activity]. Moscow [in Russian].

Bakhmach, V.O., Chekhonatskaya, M.L., Yannayeva, N.E., Zabozlayev, V.F., & Grishayeva, L.A. (2011). Izmineniya matki i sheyki matki vo vremya beremennosti i nakanune rodov (obzor) [Changes in the uterus and cervix during pregnancy and on the eve of childbirth (overview)]. Saratovskiy nauchno-meditsinskiy zhurnal – Saratov Journal of Medical Scientific Research, 2 (7), 396-400 [in Russian].

Strizhakov, A.N., Ihnatko, I.V., Timokhina, E.V., & Kardanova, M.A. (2018). Kriticheskoye sostoyaniye ploda: diagnosticheskiye kriterii, akusherskaya taktika, perinatalnyye iskhody [Fetal condition: diagnostic criteria, obstetric tactics, perinatal outcomes]. Moscow [in Russian].

Savitskiy, G.A., & Savitskiy, A.G. (2003). Biomekhanika fiziologicheskoy i patologicheskoy rodovoy skhvatki [Biomechanics of physiological and pathological labor]. Saint-Petersburg [in Russian].

Markin, L.B., Popovych, O.I., & Popovych, A.I. (2017). Doplerometrychne doslidzhennia matkovo-platsentarno-plodovoho krovoplynu u vahitnykh z pervynnoiu arterialnoiu hipotoniieiu [Doppler examination of uterine-placental-fetal hemodynamic in pregnant women with arterial hypotension]. Aktualni pytannia pediatrii, akusherstva ta hinekolohii – Actual Issues of Pediatrics, Obstetrics and Gynecology, 1, 100-104. doi: 10.11603/24116-4944.2017.1.7397 [in Ukrainian].

Rovas, L., Sladkevicius, P., & Strobel, E. (2005). Three-dimensional power Doppler ultrasound assessment of the cervix for the prediction of successful induction of labor with prostaglandin in prolonged pregnancy. J. Ultrasaund Med., 24, 933-939.

Markin, L.B., & Shatylovych, K.L. (2007). Doplerometriia v akusherstvi: hemodynamichni osoblyvosti funktsionalnoi systemy maty-platsenta-plid [Doppler in obstetrics: hemodynamic features functional system mother-placenta-fetus]. Reproduktivnoye zdorovye zhenshchiny – Reproductive Health of Women, 1 (30), 26-39 [in Ukrainian].

Mintser, O.P., Voronenko, Yu.V., & Vlasov, V.V. (2003). Obroblennia klinichnykh i eksperymentalnykh danykh u medytsyni [Treatment of clinical and experimental data in medicine]. Kyiv: Vyshcha shkola [in Ukrainian].

Published

2018-10-27

Issue

Section

OBSTETRICS AND GYNECOLOGY

How to Cite

THE ROLE OF HEMODYNAMIC PROCESSES IN CHANGES OF THE UTERUS OF PREGNANT WOMEN WITH PRIMARY ARTERIAL HYPOTENSION. (2018). Actual Problems of Pediatrics, Obstetrics and Gynecology, 2, 58-62. https://doi.org/10.11603/24116-4944.2018.2.8735