MAIN PSYCHOPATHOLOGICAL MANIFESTATIONS IN THE PRODROMAL PERIOD OF PSYCHOSIS

Authors

  • O. P. Venher I. Horbachevsky Ternopil State Medical University
  • O. Ye. Smashna I. Horbachevsky Ternopil State Medical University
  • Ya. M. Nestorovych I. Horbachevsky Ternopil State Medical University
  • Yu. I. Mysula I. Horbachevsky Ternopil State Medical University
  • L. M. Sas I. Horbachevsky Ternopil State Medical University
  • V. S. Bilous I. Horbachevsky Ternopil State Medical University
  • O. O. Liuta I. Horbachevsky Ternopil State Medical University
  • T. P. Guseva I. Horbachevsky Ternopil State Medical University

DOI:

https://doi.org/10.11603/1811-2471.2018.v0.i4.9560

Keywords:

prodromal period of psychosis, paranoid schizophrenia, acute polymorphic psychotic disorder

Abstract

The World Psychiatric Association and the European Association of Psychiatrists, as the main strategy for the treatment of psychosis in general and schizophrenia in particular, offer early detection of this pathology and timely medical intervention. Particular importance is given to early intervention in the prodromal period of psychosis.

The aim of the study – to learn the psychopathological patterns of the development of the prodromal stage of psychosis to identify the risk factors for the formation of psychosis. In the course of the study, 137 patients with the first psychotic episode were screened.

Results. The most important diagnostic features of the prodromal period of psychosis (PPP) in patients with paranoid schizophrenia are: stereotyped thinking, social isolation, disorganization thinking disorders, passive-apathy social isolation, suspicion. The most informative prodromal symptoms of acute psychosis in patients with acute polymorphic psychotic disorder are: conceptual disorganization of thinking, bizzare thinking, social isolation, suspicion / persecutory ideas, diminished expression of emotions.

Conclusions. The obtained data allows to predict in patients with acute polymorphic psychotic disorder (APPP) less progressivity of psychotic disorder, its more favorable course and the best way out.

References

Abramov, V.A., Likholetova, O.I., & Putyatin, G.G. (2012). Klinicheskiy analiz initsialnogo prodroma shizofrenii vo vremennom i genderno-vozrastnom aspektakh [Clini­cal analysis of the initial prodroma of schizophrenia in the temporal and gender-age aspects]. Zhurnal psikhiatrii i meditsinskoy psikhologii – Journal of Psychiatry and Medical Psychology, 2 (29), 15-29 [in Russian].

Skugarevskaya, M.M. (2009). Prodrom shizofrenii. Otsenka riska razvitiya psikhoza [Prodrom schizophrenia. Estimation of the risk of psychosis]. Psikhiatriya – Psy­chiatry, 4 (06), 71-79 [in Russian].

Bechdolf, A., Wagner, M., Ruhrmann, S., Harrigan, S., Putzfeld, V., Pukrop, R. et al. (2012). Preventing progression to first-episode psychosis in early initial prodromal states. Br. J. Psychiatry, 200, 22-29.

Frommann, I., Pukrop, R., Brinkmeyer, J., Bechdolf, A., Ruhrmann, S., Berning, J, ... & Wagner, M. (2011). Neuropsy­chological profiles in different at-risk states of psychosis: executive control impairment in the early and additional memory dysfunction in the late-prodromal state. Schizophr. Bull., 37 (4), 861-873.

Fusar-Poli, P., Deste, G., Smieskova, R., Barlati, S., Yung, A.R., Howes, O., … & Borgwardt, S. (2012). Cognitive functioning in prodromal psychosis: a meta-analysis. Arch. Gen. Psychiatry, 69, 562-571.

Fusar-Poli, P., Yung, A.R., McGorry, P., & van Os, J. (2014). Lessons learned from the psychosis high-risk state: towards a general staging model of prodromal intervention. Psychol. Med., 44, 17-24.

Howes, O., Montgomery, A., Asselin, M., Murray, R.M., Valli, I., Tabraham, P., … & Grasby, P.M. (2009). Elevated striate dopamine function linked to prodromal signs of schizophrenia. Arch. Gen. Psychiatry, 66, 13-20.

Jahshan, C., Heaton, R.K., Golshan, S., & Cadenhead, K.S. (2010). Course of neurocognitive deficits in the prodrome and first episode of schizophrenia. Neuropsychology, 24 (1), 109-120.

Published

2018-11-23

Issue

Section

Original research articles

How to Cite

MAIN PSYCHOPATHOLOGICAL MANIFESTATIONS IN THE PRODROMAL PERIOD OF PSYCHOSIS. (2018). Achievements of Clinical and Experimental Medicine, 4, 64-69. https://doi.org/10.11603/1811-2471.2018.v0.i4.9560