PERSPECTIVES OF APPLYING NEW APPROACHES TO THE IMPLEMENTATION OF MATHEMATICAL TECHNOLOGIES IN THE STUDY OF CELL ACTIVITY

O. I. Ryabukha

Abstract


Photographs of ultrathin sections of the studied tissues are subject to the research. According to the method of determining the profiles of specific capabilities of hormonopoietic cells, based on cytophysiology data on the functional values of individual organelles and using elements of the cluster analysis, organelles are divided into separate groups (clusters) in accordance with their specialization in the cell. While applying the method of semi-quantitative analysis of electronograms, the structure and condition of the constituent elements of each cluster are compared with those in analogous ultrastructures both in the normal range and in the studied deviations. While applying the method of semi-quantitative analysis of electronograms, grading scale performs a digital evaluation of the characteristics' severity of each cluster element. The averaged results of the cluster elements evaluation serve as the basis for establishing certain interdependencies between them, which are objectified by correlation analysis with the construction of intra-cluster (intra-system) correlation portraits. For instance, a comparative study of the synthetic capacity of follicular thyrocytes in the thyroid gland of rats is presented through the commonly used linguistic description and analysis of the constructed correlation portrait.

Suggested approach to the study of a hormonopoietic cell not only makes it possible to establish interconnections between organelles within a certain cluster and to note the peculiarities of the implementation of a certain activity direction, but also allows to search for potential and reserve capabilities of the cell, which, in its turn, significantly broadens the very idea of its functional capabilities as the basis of life of any biological object.


Keywords


mathematical technologies; cell; thyroid gland; follicular thyrocyte.

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DOI: https://doi.org/10.11603/mie.1996-1960.2018.1.8894

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ISSN: 1996-1960
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