@article{Sklyarova_Denysenko_Ilkiv_Fomenko_2016, title={Roleofgasotransmitters: nitrogen oxide and hydrogen sulfide in smool intestine of rats under cyclooxygenase and lipoxygenase inhibition}, url={https://ojs.tdmu.edu.ua/index.php/MCC/article/view/6945}, DOI={10.11603/mcch.2410-681X.2016.v0.i3.6945}, abstractNote={<p>Inexperimentstherewerecomparedthecyclooxygenaseinhibitionbyindomethacinanddualcycloocygenaseandlipoxygenaseblockageby 4-thiazolidinonederivatives, capabletoreleasehydrogensulfidein small intestine. Itwasshownthatindomethacinwasaccompaniedbytheformationoflesions in the distal part ofsmall intestine, significantactivationofinducibleNO-synthase, thedecreaseofH<sub>2</sub>Sproduction, riseinmalonicdialdehydeconcentrationand activity of myeloperoxidase. Theadministrationof5-(3,5-di-tert-butyl-4-hydroxybenzylidene)-4-thyoxo-thiazolidine-2-onand 2-[(4-chlor-phenyl-carbamoyl)-methyl]-3-(3,5-di-tert-butyl-4-hydroxyphenyl)-acrylicaciddidn’tdemonstrateanulcerogenicactioninsmallintestine, thatwasprobablycausedbythereleaseofH<sub>2</sub>S from these compounds.</p>}, number={3}, journal={Medical and Clinical Chemistry}, author={Sklyarova, Yu. O. and Denysenko, N. V. and Ilkiv, I. I. and Fomenko, I. S.}, year={2016}, month={Nov.}, pages={54–58} }