ДІАГНОСТИКА, ЛІКУВАННЯ І ПРОФІЛАКТИКА ХРОНІЧНОГО ГЕПАТИТУ C В УМОВАХ ПЕРВИННОЇ ЛАНКИ МЕДИЧНОЇ ДОПОМОГИ (ОГЛЯД ЛІТЕРАТУРИ)

S. Kh. Lapasov, L. R. Khakimova, M. Kh. Ablakulova, N. N. Ermukhamedova, D. Kh. Abdukhamidova

Анотація


РЕЗЮМЕ. У статті представлений огляд літератури з діагностики, лікування та профілактики хронічного гепатиту С в умовах первинної ланки медичної допомоги.

Висвітлено питання збору анамнезу, об'єктивного дослідження, а також методи лабораторно- функціонального обстеження, що включають біохімічні маркери – визначення аланінамінотрансферази (АЛТ), аспартатамінотрансферази (АСТ), лужної фосфатази, гамма-глутамілтрансферази, альбуміну, загального білка крові, протромбінового часу, загальних показників крові; ультразвукове дослідження печінки. Для діагностики і моніторування інфекції, викликаної вірусом гепатиту C, представлені два види досліджень: серологічні – для визначення антитіл до HCV (анти-HCV), і молекулярно-біологічні – для детекції РНК вірусу (РНК HCV). Приділено особливу увагу немедикаментозним (зміна способу життя) і медикаментозним методам лікування хронічного гепатиту С у вигляді поєднання Пег-ІФН-α-2а (пегасис) і α-2b (пегінтрон) з рибавірином (копегус).


Ключові слова


діагностика; лікування; хронічний гепатит; профілактика.

Повний текст:

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Посилання


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DOI: http://dx.doi.org/10.11603/1811-2471.2017.v0.i2.7722

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