Changes of the content of nitrogen metabolites and endothelin-1 in the oral liquid of patients with generalized periodontitis on the background of type 1 diabetes mellitus with cardiomyopathy

R. Yu. Shkrebnyuk, Yu. L. Bandrivskyі

Abstract


The work adduces the parameters of endothelial dysfunction according to indices (NO2+NO3) and endothelin-1 (ET–1) in оral serum in patients with generalized parodontitis on the backdround of diabetes mellitus type 1 with  cardiomiopathy (main group) and in persons with GP without general somatic diseases (comparative group). When comparative evaluation of frequency of change of ET-1, NO2+NO3 it was established that patients with GP on the background of diabetes mellitus type 1 with cardiomiopathy differs from patients with GP without general somatic diseases more significant changes of metabolites of nitrogen and endothelin-1, where when intensifying of processes in examined patients’ parodontium the meaning of analyzed indices characterized more pronocenced disbalance.


Keywords


generalized parodontitis; diabetes mellitus; endothelin-1.

References


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DOI: http://dx.doi.org/10.11603/2311-9624.2016.4.7231

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