Energy indexes in rats in chronic conditions of Tobacco smoke

P. H. Lykhatskyi, L. S. Fira, O. I. Kachur

Abstract


In an experiment on rats of different age groups affected by tobacco smoke me marked the activation of lipid peroxidation, which is supported by probable increase in serum, liver and lung content of TBA-active products at 30 and 45 days of the study. The intensification of this process lead’s to inhibition of mitochondrial enzymes, including cytochromeoxidase and succinated hydrogenase, which are key markers of energy processes in the organism. It was found that the most sensitive to tobacco smok is for immature animals.


Keywords


smoke; rats, bioenergetic processes; free radical processes.

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DOI: http://dx.doi.org/10.11603/mcch.2410-681X.2016.v0.i4.7253

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